NV in particular barely runs on hardware it was actually intended for.
There is a thing called Portmaster that can make both actually old PC games like Fallout 1 and 2 as well as lightweight modern games like Balatro or Stardew Valley run on these contraptions. Its device compatibility list might be a starting point.
There are also youtubers like retro game corps whose whole job is extremely detailed reviews of every new handheld game contraption that comes out.
Failing to block ads is like that except instead of cool devil Lenin it's biblically accurate Kissinger.