Came to say inFamous, but specifically picking up after the evil ending in 2. The way that frames it could allow for character customization, and maybe even getting to choose your powerset.
It could even have multiplayer elements if that's where they wanted to go with it. Not sure how well PvP would work out, but co-op missions could be fun. But, it could work just fine without any of that
This game and the OG Planetside both taught me the simple joys of fighting for/on a bridge.
You can have a huge overworld, you can have an intricate map with all the lanes and passageways you want, but, in the end, the (much, much older) children yearn for the bridge.