bandario

joined 2 years ago
[–] bandario 1 points 2 years ago

How would he know, boys aren't allowed to know about baking!!

[–] bandario 1 points 2 years ago (1 children)

For example a friend of a friend was at a party, met with a girl and she later on spilled the beans just before the sex act. She was trans and that guy gut furious

This is beyond problematic behaviour.

[–] bandario 1 points 2 years ago (3 children)

That 'others' category is a bit of a worry there, sport.

[–] bandario 2 points 2 years ago

God damn, this comment slaps.

[–] bandario 2 points 2 years ago* (last edited 2 years ago) (1 children)

I feel your frustration. I played New Super Mario Bros. Wii (2009) on an emulator recently and then New Super Mario Bros. 2 (2012). They've literally been selling the same game over and over again for full price for 15 years.

I guess I just take this in another direction. I don't yearn for some new fangled mario with better graphics, I just accept that I'm not going to pay for the same product over and over again.

[–] bandario 3 points 2 years ago (4 children)

You clearly feel a lot more strongly about this than I do.

Life is too short to play bad games. Mario wonder wasn't a bad game for me.

If your gripe is more with nintendo's increasingly poor value proposition, predatory consumer practices and litigious bullshit then there's more of a conversation to be had. I'd suggest your best revenge tools at this point are called Yuzu and Ryujinx.

[–] bandario 2 points 2 years ago (8 children)

Perhaps I'm missing the point here. What's wrong with Mario wonder?

3D Mario games have all sucked imo. It's a game that works best in 2D.

[–] bandario 2 points 2 years ago

Not a bad idea with the kayaks. I just bought a couple of old style geoff barker kayaks/ canoes from an old bloke who does that as a hobby. The old style fibreglass kayaks really lend themselves to easy and quality repair jobs. I felt like we both got a win out of the sale.

They're pretty fun on the water compared to my old plastic behemoths. So easy to load and unload and takes almost zero energy input to paddle. Bloody easy to tip them over though!

[–] bandario 0 points 2 years ago (1 children)

I can ignore a lot of things if the game still feels good: microtransactions being jammed down my throat I can ignore as long as they are not pay to win. Game modes that don't interest me, I can ignore (they even give you the option to uninstall JUST warzone if you don't play it).

The saga of COD's super aggressive SBMM and active manipulation of the result of 1v1 encounters over the last 12 months I cannot abide. Dropped frames in the middle of a close quarters battle whilst their algorithm decides which player should come out on top to maintain engagement? Nope! If this is the direction that play is headed they are beyond redemption.

Myself and many others are out here hungering for an arcade shooter that rewards player skill and movement mastery. It's only a matter of time until someone gets that formula right and takes a huge chunk out of the COD franchise.

Xdefiant, The Finals, Unrecord, Marathon are all possibilities, but you can't play any of them right now.

It's a bloody sad year for gaming imo - I prefer to play online multiplayer but since I got bored of BF 2042 and swore off of COD altogether, I am spending my time playing some of the great single player games from the last couple of years instead.

[–] bandario 1 points 2 years ago (3 children)

It's a bummer that there's nothing comparable as competition that actually has a playerbase.

There's a few on the horizon but as of right now it's a wasteland.

[–] bandario 11 points 2 years ago (3 children)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976712/

It's significant. Biggest effect is on efficacy of drug metabolism. There are many such studies.

One size does not fit all here owing to differences in expression of metabolising enzymes and drug transport mechanisms.

No, the Japanese are not aliens but they may require far less of a given drug than a westerner, or far more. This affects the likelihood to experience side effects for any given compound, and their severity.

It's fairly ironic to make this change for Japan whilst elsewhere in the world with more racially mixed populations there has been a push in the opposite direction: a recognition that you cannot assume the results of a trial carried out on white male subjects will apply to those of African descent for example.

It's not just drug treatments either. There are many aspects of medical care which have suffered from a lack of specificity and systemic bias.

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