I think I got some sort of infinite scaling with the Mandonel and Nyx's passive and I overflowed the 32-bit integer a few times. The game was frozen during that screenshot and crashed. The log showed my damage was even higher.
628.330 Game [Warning]: 10: Damage too high: 16,281,678,905,344
628.330 Game [Warning]: Victim: FlakShipAvatar5105, source: SpaceTennoAvatar4926
Thats some serious drift on the red N64 controller