I have been experimenting with using Inkscape and OpenSCAD for 3d modeling, and it seems to work for what I do, but I know quite a few people prefer a more graphical interface than OpenSCAD.
Wine can be difficult to get working right (I have tried to use Wine for a few things before and I also had issues with it that I couldn't solve), so it doesn't surprise me that it doesn't work right for you. It is a miracle that they can get any apps to run on a completely different operating system, and audio software tends to be very complicated and often depends on system APIs.
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I wonder if even just an open source firmware for printers could work.
I have a Brother printer that barely works with anything, but on Linux it works perfectly fine.
I think music production software uses some system APIs that might not even be possible to replicate with Wine or Proton.
I do not believe there is any way to change it without connecting directly to the device's circuitry, and in some widgets it may even be stored in the ROM, so a Flipper Zero would not be of much help (unless the board has some sort of programming interface you could connect to the Flipper Zero).
I am planning on writing a graphical interface for gphoto2 (a Linux camera remote library) which will allow for tethered shooting and some other neat things (like using a computer as an intervalometer). I might also write a web interface for it, so it will allow for using a table or phone to remote control a camera and allow the user to check on timelapses, but it will take a while to get it all to work.