Oh dear lord, that is my least favorite thing about pill caddies, lol. Especially when the labels have worn off, and I'm sitting there poking the braille like: "You'd think I would recognize the patterns by now, given that the labels disappeared like, a year ago..."
... actually, no, that's my second least favorite thing about pill caddies. My actual least favorite is that mine are not waterproof. Ask me how I know, lol.
My guess? Sleep deprivation. I'm not a doctor, but I personally have found that sleep debt wrecks my brain chemistry, for up to twice the number of days I got less than 8 hrs of sleep (or whatever my baseline is at that time). Losing at least an hour a night for six nights in a row would definitely make me garbage for at least a day or two, probably more like a week.
Granted, ADHD is not the only issue I have that for which this is relevant, but even NT people have trouble focusing when they're really tired, sooo...