I’m sick and came to the doctor to get tested for covid, strep, and flu, since those are going around my work. I asked the doctor if I could get paxlovid if the covid test was positive, and he goes “Oh I don’t think you’d need it”

Motherfucker almost everyone who catches covid should be fucking taking it wtf is wrong with you. Oh I’m young and otherwise healthy? Yeah and I’d like to fucking stay that way thank you very much, and I’ll take any reduction in the chance of becoming permanently disabled.

Also of the medical professionals I saw today, they were only wearing surgical masks, not N95s and I can’t comprehend it. Why in the hell would you go into the room of a likely covid case not wearing an N95 are you insane?

I’m so fucking sick of being the only person in this entire town that’s actually worried about catching this disease, even the fucking doctors don’t care anymore. I work in a research facility attached to a hospital and when I go to the food court and shit at best like 1/25 people are wearing masks. In a hospital.

Thank you Mr Joe Brandon for ending the pandemic, you’ve truly cemented your place among history’s greatest killers.

covid-cool biden-harbinger

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[–] [email protected] 1 points 2 years ago* (last edited 2 years ago) (1 children)

Is there a viable biochemical pathway for this to develop

I’m not a medical expert but a quick google search revealed medical experts fearing that is the case

Also interestingly enough I decided to google if bacterial resistance to hand sanitizer was a thing and yes apparently some bacteria are evolving tolerance of hand sanitizer.

Life will uh find a way

[–] [email protected] 10 points 2 years ago* (last edited 2 years ago)

I’m not a medical expert but a quick google search revealed medical experts fearing that is the case

Just like there were medical experts sharing that masks were not effective for the general public at the opening stages of the pandemic.

Also interestingly enough I decided to google if bacterial resistance to hand sanitizer was a thing and yes apparently some bacteria are evolving tolerance of hand sanitizer.

Bacterial 'resistance' to ethanol based hand sanitizer is not a thing so much as bacterial tolerance of alcohol concentrations can increase, and they can point to the specific biochemical pathways of concern (changes to carbohydrate metabolism). Which is not the case and cannot be the case for a lipophilic virus like SARS-CoV-2.

A quick glance at the literature indicates:

There are observed mutations in the main proteases that confer resistance to paxlovid [1][2]
These confer significant fitness penalties to the virus outside of paxlovid exposure. [2]
Due to point 2 and the rarity of these mutations, these are not expected to occur in a meaningful level outside of selection internal to immunosupressed individuals [2][3].

Yeah imma get the drug.