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This wasn't "his brain matter", these were "neuronal organoids" (clumps of neurons) grown from harvesting white blood cells and turning those into stem cells. Then the clumps were networked together with a literal wire to conduct signals between them, for timing.
Usually in organoids networks the wire delivers either regular, repeating inputs ("clean" pulses) as a reward for succeeding a task, or a random signal ("noise") for failure; this is how they're "trained" to play Pong for example:
(https://www.cell.com/neuron/fulltext/S0896-6273(22)00806-6)
These same methods are being used to train organoids as Machine Learning compute substrates, because they're much more efficient than silicon: https://aapsopen.springeropen.com/articles/10.1186/s41120-025-00109-3