this post was submitted on 14 Jun 2025
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I had a moment looking at myself in the mirror, and realized I don't like the person I see. I've been trying to change this. Therapy, changing my diet to be more healthy, etc. I've taken 10mg of Lexapro for about six months and it didn't really seem to help, it just sorta put me into a weird headspace. So my Dr bumped the Lexapro down to 5mg, and added 75mg of Wellbutrin to the mix.

I've been taking it for 4 days. I'm tolerating the Wellbutrin fine, but my appetite is fucking gone. I'm no longer really craving the stuff I used to, sweets n salts, but my appetite in general is just fucking gone. I've eaten once a day for the last 4 days. I'm downing water, and unsweetened tea like it's the cure for cancer all of a sudden. I have always drank a good amount of water, during summer I knock out at least two gallons every day.

Today I drank 3.5 gallons of water, tea, Gatorade and pedialyte. And I'm still fucking thirsty. Yesterday I had almost the same amount, killed 3 gallons and maybe a quart more. Im not dehydrated, im urinating and it's clear, but I just can't drink enough. If I shake my stomach, I can hear the water sloshing.

What the fuck? Is this normal? Should I be concerned for something else? I'm not prediabetic, no cancer anymore, I've just had a shit ton of bloodwork done three weeks ago so I'm fairly sure it's not some undiagnosed condition. Anyone else take Wellbutrin, and have this happen?

Side effect, haven't had an edible in two days, so I may end up coming out of this completely sober too, which was unexpected but completely fine.

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[–] [email protected] 3 points 6 days ago (2 children)

Wellbutrin is a stimulant, so it's not unusual to have an appetite reduction. Craving liquids like that sounds like a side effect to me. Message/call your doc and let them know, but if it's not unbearable you could wait a few days and it might go away. Your appetite might come back too after you take it for a while.

There could also be some interaction between Lexapro and Wellbutrin, but tbh you're on pretty low doses of both. Be sure to tell your doctor even if it goes away.

[–] [email protected] 3 points 6 days ago (1 children)

My Dr uses MyChart,so I sent a message. Hopefully I get a response of some sort soon enough.

It really isn't unbearable, I just kinda wanted to see if someone would just be like 'ah yeah that's Wellbutrin thirst go get a big glass of water you'll get used to it' or something like that.

[–] [email protected] 1 points 6 days ago

I take it (for 5+ years now) and drink a lot of water, but I've been drinking a lot of water for decades at this point so idk. I doubt it's anything that's gonna harm you beyond the discomfort of being thirsty all the time.