Public Health

In October 2024, the global stockpile of oral cholera vaccine (OCV) ran dry yet again, leaving no unallocated doses for new or worsening outbreaks. This underscores the ongoing shortfall of tens of millions of doses, driven by growing need, with both cases and deaths increasing globally in recent years, and lack of supply, with only one manufacturer currently serving the global stockpile. Meanwhile, however, pharmaceutical companies are reaping profits from a booming parallel market for OCV for a much lower-risk population: travelers from high-income countries (HICs). The current situation, where a tourist from a HIC at essentially zero risk of dying from cholera has more ready access to vaccines than a resident of the endemic country they will visit, exemplifies the chasm between commercial priorities and global health needs.

cross-posted from: https://lemmy.sdf.org/post/31932470

When a person dies, clinicians often look at the cause of death to determine whether it could have been avoided, either by medical prevention such as vaccines or by treatments like antibiotics. These types of deaths are known as avoidable mortalities, and in most high-income countries around the world, the number is going down.

But in the United States, avoidable deaths have been on the rise for more than a decade, according to a new study by researchers at the Brown University School of Public Health and Harvard University, who examined mortality trends across U.S. states and 40 high-income countries. Their findings were published in JAMA Internal Medicine.

There's a sizzling debate on social media over seed oils, with some people adamantly claiming they are unhealthy.

But new research, which expands on previous studies in this area, finds that they could reduce your risk of an early death.

Adding fuel to the social media controversy is Robert F. Kennedy Jr., secretary of the U.S. Department of Health and Human Services, who has also taken aim at seed oils.

In October, he posted on social media platform X, claiming that seed oils are poisoning Americans and are a driving cause of obesity.

Health experts continue to push back, saying seed oils are, in fact, not toxic. And they say it's processed foods, not the oils themselves, that are the problem.

I'm unfamiliar with this topic so I don't want to comment further, here are some key excerpts from the article:

Findings Our search identified 2037 studies, of which 42 peer-reviewed articles and nine grey literature reports met inclusion criteria: these studies were in Canada (n=3), Australia (n=17), New Zealand (n=9), and the USA (n=22). With the exception of Māori children in New Zealand, who seem to have similar rates of epilepsy to children of European ancestry, the incidence and prevalence of epilepsy seemed to be higher in Indigenous peoples in these regions than non-Indigenous populations. In the included studies, Indigenous peoples showed a higher number of epilepsy hospital presentations, decreased access to specialists, decreased access and longer waits for antiseizure medication, and increased prescriptions for enzyme-inducing antiseizure medications when compared with non-Indigenous peoples. In Australia, the number of disability-adjusted life years among Aboriginal and Torres Strait Islander peoples with epilepsy was double that for non-Indigenous people with epilepsy. Mortality rates for Indigenous peoples with epilepsy in New Zealand and Australia were higher than in non-Indigenous people with epilepsy.

Interpretation Although Indigenous people from CANZUS have unique cultural identities, this review identified similar themes and substantial disparities experienced by Indigenous versus non-Indigenous people in these nations. Concerningly, there were relatively few studies, and these were of variable quality, leaving substantial knowledge gaps. Epidemiological epilepsy research in each specific Indigenous group from CANZUS countries is urgently required to enable health policy development and minimise inequity within these countries.

Excerpt of the summary:

Childhood diseases have profound lifelong effects on health, livelihoods, and societies. Investment in early childhood results in highly cost-effective changes to lifelong health, productivity, and human capital returns. Yet, there remain substantial gaps in knowledge on the efficacy and safety of many paediatric interventions, which represents a failure to establish shared priorities and alignment across governments, researchers, communities, and funders. Children are frequently marginalised from clinical trials, which is an issue of equity. Challenges include mismatched priorities and funding, risk adversity, poor design, power imbalances, and inadequate infrastructure.

Some graphs:

Figure 2 Demographic characteristics of paediatric clinical trials 2020–23

Figure 3 Registered paediatric clinical trials by country (2020–23)

The study, which analysed data from 26 countries, found that if international support declines, an additional 4.43 to 10.75 million new HIV infections – including up to 880 000 in children – could occur by 2030. In the same period, 770 000 to 2.93 million more people could die from HIV-related causes, with up to 120 000 of these deaths affecting children.

Author:

• Brenda Vrkljan | Professor of Occupational Therapy, School of Rehabilitation Science, McMaster University

Kim’s son Zack was diagnosed with a glioblastoma multiforme. It is a brain tumour that is very rare in children and is usually seen in adults over 45.

Zack had chemotherapy treatments but doctors said there was no hope of him ever recovering. He died at just six years old.

Years later, social media and community chatter made Kim start to think that her son was not an isolated case. Perhaps he was part of a bigger picture growing in their community surrounding Coldwater Creek.

In this part of the US, cancer fears have prompted locals to accuse officials of not doing enough to support those who may have been exposed to radiation due to the development of the atomic bomb in the 1940s.

A compensation programme that was designed to pay out to some Americans who contracted diseases after exposure to radiation expired last year - before it could be extended to the St Louis area.

Here is a small summary, there is additional context in the article

Community partners advocated for research queries to support greater policy impact

Researchers used community input to design Advanced Clean Truck (ACT) air-quality model experiments. Community asked for ACT policy simulations that convert 48% of medium- and heavy-duty vehicles into zero tailpipe emission versions. Researchers simulated how this policy would change pollution levels in Illinois. They found the policy would likely prevent 500 premature deaths and 600 new pediatric asthma cases annually within the greater Chicago area.