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Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.

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Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01827-0

Jayanta Bhattacharya says the US biomedical agency can’t continue ‘business as usual’ if it wants to restore its reputation.


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27
 
 

Nature, Published online: 12 June 2025; doi:10.1038/d41586-025-01835-0

Your inhalation and exhalation pattern is not only unique to you, it can be a marker of your physical and mental state, study suggests.


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28
 
 

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01850-1

The flexible implant measures brain activity during embryonic development in amphibians — plus, a new way to restore damaged paintings with the help of AI.


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29
 
 

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01836-z

The new method could be 70 times faster than repairing painting by hand.


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30
 
 

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09112-w

A several-fold reduction in temperature is accomplished using a neutral-atom Hubbard quantum simulator by transforming a low-entropy product state into strongly correlated states of interest via dynamic control of the model parameters.


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31
 
 

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-08963-7

A two-dimensional one instruction set computer has been fabricated based on complementary metal–oxide–semiconductor technology by leveraging the heterogeneous integration of large-area n-type MoS2 and p-type WSe2 field-effect transistors.


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32
 
 

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09105-9

Strong lasing effects similar to those in the optical regime can occur at 1.5–2.1 Å wavelengths during high-intensity XFEL-driven Kα1 lasing of copper and manganese.


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33
 
 

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09032-9

The facile synthesis and spectroscopic identification of previously unreported hexanitrogen C2h-N6 is described, representing experimentally realized neutral molecular nitrogen allotropes beyond N2 that exhibit unexpected stability.


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34
 
 

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09045-4

A digital restoration technique for damaged paintings was developed, in which a colour-accurate bilayer mask of printed pigments on polymeric films was used, reducing treatment time and cost while adhering to ethical conservation principles.


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35
 
 

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01779-5

Experiments in mice reveal an early postnatal window of opportunity for the effective transfer of genes to blood-cell-producing haematopoietic stem cells by injecting mice with gene-carrying lentiviral vectors. This approach showed therapeutic benefit in three mouse models of severe diseases, and could expand the applicability of haematopoietic stem-cell gene therapy in the clinic.


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36
 
 

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01451-y

A quantum random-number generator has been developed that uses classical cryptography to certify that its output was produced by a quantum process.


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37
 
 

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01798-2

Massive telescope will map the Universe and provide an evolving record of the Solar System and distant stars.


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38
 
 

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01799-1

Researchers reveal when boys pull ahead of girls in mathematics, sounding an alarm and providing both an opportunity for schools, parents and researchers.


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39
 
 

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01785-7

The mapping of lake surfaces globally has been constrained by the limitations of single-source satellite data. A spatio-temporal fusion approach now enables high-resolution mapping of more than 1.4 million lakes, revealing seasonality as the main factor driving changes in the spread of lake surfaces, with links between seasonality and human residence.


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40
 
 

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01453-w

These prototype processors made from atomically thin materials offer a glimpse into a post-silicon-transistor future, but scaling challenges remain.


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41
 
 

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01583-1

A key component of the TCA cycle, a series of reactions that occurs in energy-generating organelles called mitochondria, can dictate the fate of intestinal stem cells.


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42
 
 

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01752-2

Neuroscientists have found the regions that keep them apart.


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43
 
 

Nature, Published online: 12 June 2025; doi:10.1038/s41586-025-09127-3

A brain-to-voice neuroprosthesis enables a man with amyotrophic lateral sclerosis to synthesize his voice in real time by decoding neural activity, demonstrating the potential of brain–computer interfaces to enable people with paralysis to speak intelligibly and expressively.


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44
 
 

Nature, Published online: 12 June 2025; doi:10.1038/d41586-025-01646-3

Salah Obayya works to advance women’s research careers in photonics in Egypt.


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45
 
 

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01801-w

In mice, engineered immune cells shrink pancreatic and other tumours bearing a mutant version of the KRAS protein.


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46
 
 

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01769-7

Building scientific capacity in the global south is key to solving today’s most pressing planetary challenges.


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47
 
 

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09152-2

The antiviral protein SP140 negatively regulates Ifnb1 mRNA stability by directly repressing the expression of the immune regulator RESIST.


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48
 
 

Nature, Published online: 10 June 2025; doi:10.1038/d41586-025-01826-1

An open collection of tips and tools could help researchers and publishers to pick up on problematic research.


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49
 
 

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09162-0

Lipoprotein uptake dependent on sulfated glycosaminoglycans linked to cell-surface proteoglycans is a key determinant of ferroptosis sensitivity in cancer.


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50
 
 

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09091-y

Certain RIFINs from Plasmodium falciparum can bind to both inhibitory (KIR2DL1) and activating (KIR2DS1) immune receptors on natural killer cells, demonstrating the potential role of activating killer immunoglobulin-like receptors in targeting pathogens and controlling malaria infection.


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